Are Steroid Eye Drops Bad for You and How Long Can I Use Steroid Eye Drops For

Steroid eye drops are bad for you if you use them for more than 10-14 days. Steroid Eye Drops can be really bad if you are a Steroid Responder or have a Steriod Response. 

Between 30% to 40% of all normal adults are steroid responders whose Steroid Response will cause hypertension in the eye. Special Population Groups who have other Chronic conditions are also at increased risk.

 Steroid Responder

Causes of Increased Eye Pressure and the Risks Associated With Increased Eye Pressure

How long you use steroid eye drops will affect your eye and general health over time.

Regular “Monitoring” of IOP among certain Special population groups may prove fruitless if Eye Pressure has spiked and Ocular Nerve damage has already occurred.

It is crucial in such cases, to use Hypochlorous Acid Eye drops as an alternative or adjunct in order to reduce the risk of almost certain IOP.

Steroid Eye Drops side effects can range from mild irritation to more serious issues like increased intraocular pressure, which can lead to glaucoma.

Many people are unaware of the risks associated with short-term and long-term use of steroid eye drops. We may rely on these medications for relief, but it’s crucial to weigh the benefits against possible complications.

Learning about safe use and alternatives can reduce your risks while effectively managing your symptoms.

Key Takeaways

  • Steroid eye drops can cause side effects, including increased intraocular pressure, especially if it is a young child or the person has been using Steroid eye drops for a long period of time.
  • Awareness of risks helps us use these drops safely and effectively.
  • Exploring alternatives can provide options for managing eye conditions.

Understanding Steroid Eye Drops

Steroid eye drops are important medications that help treat various eye conditions like Uveitis. They are used to treat eye inflammation and act quickly, but these drops carry the risk of side effects. Side effects include increased eye pressure and eye problems like vision loss.

Role and Benefits

Steroid eye drops are a traditional treatment for inflammation in the eyes. This inflammation can be due to allergies, infections, or after surgery. By reducing swelling and redness, these drops can help improve comfort and prevent damage.

Some key benefits include:

  • Reduction of Inflammation: They effectively lower swelling and redness, allowing for quicker recovery.
  • Pain Relief: They can decrease discomfort caused by eye conditions.

Key drawback of Steroid Eye Drops:

RETARD Healing: These drops do not promote better healing of injuries or surgical sites, since they have an adverse effect on the cells and collagen in the eye.

It is essential to use these drops as directed. Long-term use can lead to side effects.

 Steroid Eye Drops Effect Healing

Common Types and Preservatives

There are various types of steroid eye drops. Some contain preservatives, while others are preservative-free.

Common types of steroid eye drops include:

  • Hydrocortisone eye drops: Often used for mild inflammation.
  • Prednisolone eye drops: Frequently prescribed for moderate to severe inflammation.
  • Dexamethasone eye drops: Used for serious conditions and inflammation.

Steroid Eye Drop Indications and Steroid Eye Drop Contraindications

Steroid eye drops are commonly prescribed for several medical conditions including for Uveitis. Understanding when to use them and when they should be avoided is essential.

Therapeutic Uses

Steroid eye drops are primarily used to reduce inflammation and treat related to various eye conditions including:

  • Allergic Conjunctivitis: These drops help manage symptoms related to eye allergies.
  • Uveitis: They can treat inflammation of the uvea, a part of the eye that can become swollen.
  • Post-Surgery Care: After cataract surgery, steroid drops may be prescribed to reduce swelling and as an antiinflammatory.
  • Autoimmune Conditions: Conditions like Sjögren’s syndrome can cause eye discomfort, and an eye doctor may prescribe prednisolone eye drops to provide relief.

Steroid Eye Drop Contraindications

Certain situations make the use of steroid eye drops unsafe. We must avoid using them if we have:

  • Viral Infections: If the patient has a viral infection such as herpes simplex, these drops can worsen the condition.
  • Fungal Infections: They should not be used when a fungal infection is present in the eye or surrounding areas as it can cause the condition to get worse.
  • Glaucoma: Patients with glaucoma may experience increased intraocular pressure from these drops.
  • Allergic Reactions: If someone shows hypersensitivity or has an eye irritation to any component of the drops, they should not use them. An Hypochlorous Acid suspension or HOCL eye drop solution should be used instead.
  • Special Populations: Long periods of use and certain health issues predispose individuals to increased risk of eye health damage. read more below
  • Steroid Eye Drops
  • Length of Time of use: According to Dr Douglas Rhee a Molecular Biologist and Glaucoma Specialist, there is a direct correlation between the increased risk of adverse effects and vision loss and the length of time of use of steroid drops.

Special Populations

Steroid Eye Drops During Pregnancy

During pregnancy, women should be cautious, since steroids can affect the developing fetus. Additionally, individuals with conditions like diabetes, glaucoma, or hypertension should discuss the potential risks with their doctors. Tailoring our approach to these special populations ensures safer outcomes when using steroid eye drops.

How to Relieve Eye Pressure at Home

Steroid Drops in Children

Children, especially those under 10 years old, show a stronger intraocular pressure response.

## Example Scenario

 Let’s imagine a patient, aged 9, who has been prescribed a moderate-strength steroid eye drop for an inflammatory eye condition. This patient also has a history of high myopia and juvenile rheumatoid arthritis. Given these risk factors:

– **Risk Assessment**: The child is at a heightened risk of developing steroid-induced glaucoma due to their age, existing conditions, and the prescribed steroid therapy.

  • In children, we must be especially cautious because their developing eyes may react differently to steroids. see below
  • Be aware that the risks increase substantially in children when a child has an Autoimmune diagnoses and the probability that steroid eye drops will be prescribed throughout their lifetime with an accumulative negative effect. Steroid eye drop use that starts young has a long-term prognosis that is NOT good, since steroid eye drops are not recommended if required for 10 days or longer.
  • Juvenile Idiopathic Arthritis, which includes a subset known as Rheumatoid Arthritis, can lead to Uveitis; and Ophthalmologists often prescribe prednisone eye drops without adequately discussing their side effects or being aware of an alternative. Use the drops with great caution, since HOCL eye solutions are a way safer alternative, with a much higher therapeutic index.
  • Key Risk Factors and Causes of Increased Eye Pressure or Ocular Hypertension

     Below is a comprehensive list of the risk factors associated with a steroid response, particularly in relation to elevated intraocular pressure:

   1. High Myopia

      Meaning: Nearsightedness where distant objects appear blurry.

      Connection: High myopia can alter the structure of the eye, making it more susceptible to changes in IOP.

  2. Type 1 Diabetes Mellitus

       Description: Chronic condition characterized by high blood glucose levels due to the body’s inability to produce insulin.

       Connection: It can exacerbate the eye’s sensitivity to steroids, possibly leading to increased IOP.

   3. Connective Tissue Disorders

        Examples: Rheumatoid arthritis, Juvenile Idiopathic Arthritis and  Lupus.

        Connection: These disorders can affect the eye’s structural components, influencing the response to steroids.

     4. Pigment Dispersion Syndrome

          Description: Condition where pigment granules detach from the iris and deposit on other structures within the eye.

          Connection: These granules can impede fluid drainage, increasing the impact of steroid therapy on IOP.

      5. Traumatic Angle Recession

          Description: Injury-related condition affecting the drainage angle of the eye.

          Connection: Alters the normal ocular fluid dynamics, potentially enhancing the steroid response.

      6. Primary Open-Angle Glaucoma

           Description: The most common form of glaucoma, characterized by a gradual increase in eye pressure.

           Connection: Individuals with this condition are inherently at risk of further IOP increases due to steroids.

        7. Prior Penetrating Keratoplasty

            Description: A surgical procedure (corneal transplant) which can affect eye pressure regulation.

            Connection: Surgery may predispose the eye to greater sensitivity to steroids.

  • Regular Eye Exams

  • DO NOT be lulled into a false sense of security when told that monitoring is crucial to prevent potential complications. Especially if you are in any of the special population groups above.
  • Eye exams and regular visits to monitor your eye pressure is not a guarentee and can not monitor a dynamic change in pressure inside the eye which can cause permanent damage to the optic nerve.
  • Ensure that you understand the added risks if you are considered a Special Population member. see below
  • Do not be afraid to call your doctor right away and and to ask to prescribe newer safer alternatives and your desire to use these instead.
  • HOCL eye drops approved by the FDA in the US are the best non-steroidal anti-inflammatory eye drops for eye diseases like Uveitis and do not cause increased pressure in the eye.
  • HOCl Eye drops contain Hypochlorous Acid and are approved as a Medical Device in South Africa. This ensures strict sourcing guidelines and relies on solid Scientific evidence because results matter.
  • Academic Research Institutions have a vast body of relevant studies regarding the potency and healing effects of HOCL and HOCL eye drops that are safe for eyes.

Steroid Eye Drop Side Effects

 These effects can impact both the eyes and the body as a whole.

Other Ocular Adverse Effects

Steroid eye drops used by Opthalmologists are an established treatment for inflammation dating back to the 1950’s.

In up to 40% of individuals side effects can occur that range from mild to severe. Common issues include:

  • Increased Eye Pressure: An increase in eye pressure inside your eye will result in Gluacoma  over time. Glaucoma has long been considered “the sneak thief of sight” and is responsible for 15% of preventable blindness cases around the world.
  • Cataracts: Long-term use can also cause cataracts, which cloud the lens of the eye and cause vison loss.
  • Blurred Vision: Some users of steroid eye drops experience blurry vision after applying the drops.
  • Infection Risk: Steroids can increase susceptibility to eye infections, as they suppress the immune response.

Systemic Repercussions

Beyond ocular effects, steroid eye drops can cause systemic side effects. These may include:

  • Headaches: Some users report mild to moderate headaches after starting treatment.
  • Weight Gain: Prolonged use may lead to an increase in appetite, resulting in weight gain.
  • Mood Changes: Users might experience changes in mood and in some individuals steroid eye drops cause increased anxiety and insomnia.
  • Adrenal Suppression: In rare cases, the body’s hormone production may be affected.

It’s important to avoid symptoms and discuss new alternatives with your doctor if you are at risk. Alternative non steroidal eye drops with HOCl would be a more suitable option.

Role in IOP and Glaucoma

Steroid eye drops can significantly impact intraocular pressure (IOP). The increased pressure and the advancement of vision loss may go undetected.

Normal Pressure Glaucome

Understanding this relationship is key for individuals, especially those at risk for glaucoma. We must consider how these medications affect IOP and what that means for managing eye health. Suggesting alternatives like Hypochlorous Acid Eye drops are imperative.

Impact on Eye Pressure

In the realm of ophthalmology, **steroid response** refers to the increase in intraocular pressure (IOP) following steroid therapy, which can lead to conditions such as glaucoma.

Steroid eye drops often cause an increase in intraocular pressure. This rise in pressure can happen within a few days of starting the treatment. The extent of the increase varies among individuals. Some people may experience a minor rise, while others may have a more pronounced rise.

As the pressure increases, it can become problematic. High IOP is a main risk factor for advancing glaucoma. Continuous use of steroid drops can lead to a persistent increase in eye pressure, potentially worsening conditions for those already diagnosed with glaucoma. Regular monitoring of IOP is a poor option with poor outcomes with these drops.

See HOCL eye drops for further information.

Managing Risk for Glaucoma Patients

For patients with glaucoma, careful management of steroid eye drops is crucial. Some patients might use additional medications that help lower eye pressure naturally.

How Can I Prevent Glaucoma

Prevent Glaucoma by using HOCL eye drops to better manage both IOP and your overall eye condition while avoiding risks associated with steroid use.

How to Prevent Glaucoma

Other Risks and Considerations

Steroid eye drops can offer relief but also come with risks we should consider. Two significant areas concern how these drops may affect our blood pressure and the special groups of people who might face heightened dangers.

Blood Pressure and Systemic Health

Using steroid eye drops can potentially lead to increased blood pressure. The steroids can act on the body beyond the eyes, affecting blood vessels and fluid retention. This might not only cause hypertension but can also worsen existing heart conditions.

We need to monitor blood pressure regularly, especially for those already at risk. If we notice any significant changes, consulting a healthcare professional is essential. Keeping track of our overall health helps us use these medications safely.

In the realm of Ophthalmology, **steroid response** refers to the increase in intraocular pressure (IOP) following steroid eye therapy, which can lead to conditions such as glaucoma. This response occurs due to various risk factors. Let’s explore these factors in detail.

Special Population groups may face heightened risks when using steroid eye drops. This includes elderly individuals, pregnant women, children and those with pre-existing health conditions. For example, older adults often have reduced tolerance to medications, increasing the chance of side effects.

Steroid Eye Drops and BAK or Benzalkonuim

If you have a condition like Chronic recurring Uveitis you should be aware that the risk factors increase when using Steroid Eye Drops beyond 14 days. You should take care to reduce further complications by avoiding preservatives like Benzalkonium Chloride. BAK has fallen out of recently as it has been implicated in corneal and conjunctival surface changes, ocular discomfort, tear film instability, conjunctival inflammation, subconjunctival fibrosis, and epithelial apoptosis. It has also been inferred that BAK damages the trabecular meshwork as well.

We should consider the need for preservative-free formulations to avoid irritation. Many people who use eye drops regularly prefer these to maintain comfort and avoid side effects.

Choosing Safer Options

When considering alternatives to steroid eye drops, we have some options that may minimise side effects. We can look into treatments without preservatives and over-the-counter choices that might suit our needs better.

Alternative Treatments Without Preservatives

Certain steroid eye drops are formulated without preservatives, such as Benzalkonium chloride. Preservative-free options tend to be gentler on our eyes, reducing irritation and redness.

Examples of preservative-free drops include loteprednol and prednisolone. For those of us who need treatment for allergic reactions or inflammation, these drops can be effective.

They are especially suitable for long-term use, as they decrease the risk of developing complications over time. These options are often recommended for children, as their eyes are more sensitive to harsh chemicals.

Over-the-Counter Options

We can also find anti-inflammatory eye drops that are Homeopathic eye drops and herbal eye drops like Similisan eye drops and Dr Vogel Eye drops are available without a prescription. These over-the-counter eye drops options can be helpful for mild eye issues like allergies or dryness.

Using over-the-counter steroid eye drops are not available in South Africa.

Best Practices and Precautions

When using steroid eye drops, it is essential to be aware of the risks versus the rewards. Adhering to correct dosages and reducing long-term exposure can help ensure safe and effective treatment.

Dosage and Administration

We must carefully follow the prescribed dosage when using steroid eye drops. Incorrect dosing can lead to complications, including increased eye pressure and potential worsening of our condition.

We should apply the drops in the lower eyelid pocket rather than directly onto the eyeball.

If soreness or a sore throat develops after use, contact your healthcare provider for guidance and discuss alternatives.

Monitoring and Follow-Up

Regular monitoring is vital when on steroid eye drops. We should keep track of any side effects such as irritation, increased sensitivity, or nausea. If our symptoms worsen, we must inform our doctor promptly.

Follow-ups allow our healthcare provider to check for complications like increased intraocular pressure.

During these visits, we should discuss any concerns, including changes in vision or new symptoms. It is also wise to suggest alternatives treatments to reduce exposure to long-term steroid use. This is especially true if you fall into a Special Population – see above

Frequently Asked Questions

We often receive questions about steroid eye drops and their effects.

What are the potential systemic adverse effects of ophthalmic steroids?

Systemic adverse effects can occur when steroid eye drops enter the bloodstream. These may include increased blood pressure, increased blood sugar levels,  potential effects on bone health and vision loss.

What are the most severe complications associated with prednisolone ophthalmic solutions?

Severe complications from prednisolone eye drops can include glaucoma, cataract formation, and infections and these issues can lead to significant vision loss.

What are the consequences of extended usage of ophthalmic corticosteroids?

Extended use of corticosteroid eye drops may lead to elevated intraocular pressure, increasing the risk of glaucoma. Long-term use can also change the structure of the eye and affect vision quality.

What are the symptoms associated with cessation of steroid eye drop therapy?

Stopping steroid eye drop therapy suddenly can cause rebound inflammation. Symptoms may include redness, discomfort, and blurred vision as the body readjusts.

Can ophthalmic steroids lead to heightened anxiety?

Some patients report experiencing anxiety or mood changes while using ophthalmic steroids. These effects may vary from person to person and can depend on the dosage and duration of use.

How long is considered safe for the utilisation of corticosteroid eye drops?

The safe duration for using corticosteroid eye drops is up to 10  days or two weeks. Beyond two weeks side-effects become more pronounced and vary from individual to individual because of Genetics. Generally, practitioners recommend limiting use to the shortest duration possible, often a few weeks, unless directed otherwise for Uveitis. Finding alternatives like HOCL eye drops can help reduce exposure to steroids and their risks.

author avatar
Bernandine Johnstone CEO and Medical Device Team Leader
Bernadine is an accomplished entrepreneur and medical device developer with over 20 years of experience in biotech. Diagnosed with uveitis in 1998 and in steroid-free remission since 2008. Passionate about natural healing, Bernadine is dedicated to empowering others to help them navigate their health challenges.