Secondary Glaucoma, secondary Cataract and Optic Nerve damage are most common causes of avoidable visual impairment in patients with Chronic Uveitis, which we believe is a treatable entity. The relationship with chronic inflammatory activity and the ease with which this can be treated, confirms the importance of a safe and effective anti-inflammatory Bettamed™ Ocusolve’s inclusion in any treatment regime.
Bettamed OcuSolve Eye Drops are a life-altering advance in Uveitis Care. Our patented ECA Technology, mimics the same Oxychlorine composition as that manufactured by neutrophils in the body’s immune system.
Bettamed Ocusolve (with Hypochlorous Acid) is naturally produced by our white blood cells and is an essential part of our immune system. This process is called phagocytosis and is one of nature’s symbiotic actions- with no evidence of induced microbe resistance.5
Bettamed OcuSolve™ with (HOCl) exhibits potent broad-spectrum antimicrobial activity, including antibiotic-resistant strains of bacteria (including MRSA and VRE), viruses, fungi and spores- as demonstrated in numerous studies1,2,5,6,8,12,13, while reducing inflammation and increasing Oxygen (O2) in treated tissue.
There are no concerns about ocular toxicity with HOCL, in fact it has been found to be non-irritating and non-sensitising in various animal safety models.5
Bettamed OcuSolve™ is bio-compatible, non-toxic and non-sensitizing, making it safe for regular use.
As part of the immune response to microbial proliferation, mast cells flood the infection site, contributing to inflammation.
A significant portion of HOCl’s potency is derived from its anti-inflammatory effects, as a result of its modulating effect controlling mast cell response.
A study by Medina-Tamayo et al43 suggests a neutral PF Superoxidised Solution (SOS), acts like a mast cell membrane stabilizing inhibitor, inhibiting the cell machinery for granule secretion, without altering the signal transduction pathways. Additionally, many studies, including Sakarya et al44 demonstrate that HOCl induces significant healing, as well as a substantial reduction in signs of inflammation.
In 2013, Pelgrift et al45 proposed that HOCL is both antimicrobial and anti-inflammatory, which accounts for the reduction in pruritis in dermatology.
A study by Bongiovanni46 investigated the micro-circulatory integrity (oxygenation) of patients with venous leg ulcers and its effect on time to wound healing. Exposure of the Venous leg ulcers to HOCl elevated TcPO2 levels for up to 72 hours after exposure, which increased time to wound healing between 2-180 days.
The added advantage is that the dissolved Oxygen (O2) in Bettamed Ocusolve eye drops, improves Oxygen balance for infection control, creating a reversal of the tissue damage and possible vision loss caused by uncontrolled inflammatory processes.47,48,49